Atg8: Autophagy protein Atg8 ubiquitin like
| PAG Title | Atg8: Autophagy protein Atg8 ubiquitin like |
| PAG ID | PEX001858 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | Light chain 3 is proposed to function primarily as a subunit of microtubule associated proteins 1A and 1B and that its expression may regulate microtubule binding activity 1. Autophagy is generally known as a process involved in the degradation of bulk cytoplasmic components that are non-specifically sequestered into an autophagosome, where they are sequestered into double-membrane vesicles and delivered to the degradative organelle, the lysosome/vacuole, for breakdown and eventual recycling of the resulting macromolecules. The yeast proteins are involved in the autophagosome, and Atg8 binds Atg19, via its N-terminus and the C-terminus of Atg19. |
| Species | Homo sapiens |
| nCoCo Score | 126 |
| Base PAG ID | PEX001858 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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